AivoCode · San Diego, CA

Scientist I/II,
Neurobiology

Assay development for screening therapeutic candidates for neurodegenerative disease
Full-time
On-site · San Diego, CA
AD · MS · ALS focus

AivoCode is a neuroscience-driven biotech on a mission to transform how neurological diseases are treated and managed. We build innovative platform technologies that bridge the gap between cutting-edge neuroprotective science and real-world clinical impact — targeting some of the most challenging neurodegenerative and neurological conditions facing patients today. At AivoCode, scientific rigor and a spirit of collaboration power every breakthrough we pursue.

We are looking for a motivated and skilled Scientist I to join our Neurobiology team in San Diego. In this full-time, on-site role, you will be at the forefront of our discovery efforts — running cell-based studies that probe the therapeutic potential of our pipeline candidates across glial cell types implicated in Alzheimer's disease.

Own the full experimental cycle — from hypothesis to data to insight — evaluating the activity and mechanism of our novel peptide and biologic candidates in neural systems.

  • Establish and sustain high-quality primary neuronal and glial cultures — neurons, astrocytes, and microglia — as core experimental platforms.
  • Deploy a broad toolkit of molecular and biochemical techniques, including RT-PCR, qPCR, SDS-PAGE, Western blotting, immunocytochemistry, immunohistochemistry, and microscopy, to rigorously characterize therapeutic effects.
  • Interrogate key molecular pathways governing neuroinflammation and cellular stress, translating mechanistic findings into actionable insights for the program.
  • Stay current with the scientific literature, communicate experimental strategies and results clearly in team settings, and maintain thorough, well-organized project documentation.
Master's or PhD in Neuroscience, Neurobiology, or a closely related field.Industry exp. a plus
Hands-on experience maintaining in vitro neuronal and glial cultures.
Strong command of molecular and imaging assays — RT-PCR, qPCR, SDS-PAGE, immunostaining, confocal microscopy.
Demonstrated experience in neurodegenerative disease pathways or cellular stress and neuroinflammation mechanisms.
Excellent organizational skills with a disciplined approach to documentation and project tracking.
Familiarity with drug discovery and development workflows.A plus
⚑ Candidates must be legally authorized to work in the United States. Visa sponsorship is not available for this position.
AivoCode  ·  San Diego, CA  ·  Full-time, On-site
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